Administration Policy

Read e-book online 2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial PDF

By John S. Bradley MD, John D. Nelson MD Emeritus

ISBN-10: 1581104294

ISBN-13: 9781581104295

This best-selling and normal source on pediatric antimicrobial treatment offers immediate entry to trustworthy, up to the moment techniques for therapy of all infectious illnesses in kids. for every disorder, the authors supply a remark to assist well-being care prone choose the simplest of all antimicrobial offerings. Drug descriptions conceal all antimicrobial brokers on hand this present day and contain whole information regarding dosing regimens. in accordance with transforming into matters approximately overuse of antibiotics, this system comprises guidance on whilst to not prescribe antimicrobials. Key positive aspects: designed if you happen to look after young children and are confronted with judgements on a daily basis; comprises remedy of parasitic infections and tropical drugs; up-to-date anti-infective drug directory, whole with formulations and dosages; and balanced info on security, efficacy, and tolerability with facts on expenditures and availability of drugs.

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Extra resources for 2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy

Example text

Consider adding amox/clav or clindamycin for severe disease with oral flora superinfection. indd 43 Larger dosages may lead to tissue invasion by Aspergillus. 5 mg/kg every other day aspergillosis – Primary, putrid (ie, foul- Clindamycin 40 mg/kg/day IV div q8h OR meropenem Alternatives: imipenem IV, or pip/tazo IV, or ticar/ smelling; polymicrobial 60 mg/kg/day IV div q8h x 10 d or longer (AIII) clav IV (BIII) infection with oral aerobes and anaerobes)101 Abscess, lung – Primary (severe, necrotizing Empiric therapy with ceftriaxone 50–75 mg/kg/day For severe CA-MRSA infections, see Chapter 4.

AIII) 21 d. CT scan to confirm cure. 5 mg/kg/day IM, IV, or amikacin 15–20 mg/kg/ alternatives (no clinical data). Very poor outcomes. day IM, IV div q8h x 10–14 d (AIII) Ceftriaxone 50 mg/kg q24h IV, IM (AIII) Treatment course x 10–14 d – Staphylococcal Vancomycin 40 mg/kg/day IV div q8h pending susceptibility testing; oxacillin 150 mg/kg/day IV div q6h if susceptible (AIII) – Empiric therapy following Vancomycin 40 mg/kg/day IV div q8h AND ceftazidime open globe injury 150 mg/kg/day IV div q8h (AIII) Endophthalmitis56,57 NOTE: Subconjunctival/subtenon antibiotics usually needed; steroids commonly used; Refer to ophthalmologist; vitrectomy may be necessary for requires anterior chamber or vitreous tap for microbiological diagnosis advanced endophthalmitis Dacryocystitis No antibiotic usually needed; oral therapy for more Warm compresses; may require surgical probing of symptomatic infection, based on Gram stain and nasolacrimal duct culture of pus; topical therapy as for conjunctivitis may be helpful Conjunctivitis, herpetic54,55 Trifluridine 1% ophth soln OR acyclovir 3% ophth Refer to ophthalmologist.

Indd 42 Pharyngitis Amoxicillin 50–75 mg/kg/day PO, either once daily, bid Amoxicillin displays better gastrointestinal absorption (group A streptococcus) or tid x 10 d OR penicillin V 50–75 mg/kg/day PO div than oral phenoxymethyl penicillin; the suspension is 7,91–93 tonsillopharyngitis bid or tid, OR benzathine penicillin 600,000 units IM better tolerated. 2 million units IM if >27 kg, as a by the increased spectrum of activity that is not needed. single dose (AII) Once daily amoxicillin dosage: for children >3 years of For penicillin-allergic children: erythromycin (estolate at age and <40 kg: 750 mg once daily; for those >40 kg, 20–40 mg/kg/day PO div bid to qid; or ethylsuccinate 1,000 mg once daily.

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2010-2011 Nelson's Pocket Book of Pediatric Antimicrobial Therapy by John S. Bradley MD, John D. Nelson MD Emeritus


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